Toxicologic Biomarkers

by Anthony P. DeCaprio (Editor)

Overview

Responding to the explosion of advances in the use of biomarkers to efficiently, rapidly, and economically evaluate the health effects of chemical entities, this authoritative reference provides a detailed overview of the theory, development, and practical application of biomarkers in the toxicological, environmental, forensic, and pharmaceutical s

Product Details

ISBN-13:	9781000611823
Publisher:	CRC Press
Publication date:	04/18/2006
Sold by:	Barnes & Noble
Format:	eBook
Pages:	312
File size:	3 MB

About the Author

ANTHONY P. DECAPRIO is Professor of Environmental Health Sciences, University of Massachusetts, Amherst. Previously, he served as Director of the Exposure Assessment Laboratory, University of Albany, New York, and as a Research Scientist in the Laboratory of Human Toxicology and Molecular Epidemiology for the New York State Department of Health. His research interests include the theory and practical use of biomarkers in exposure analysis, the toxicology of persistent organic pollutants, and the application of macromolecular modifications (DNA and protein adducts) in human exposure and toxicological safety assessment. Dr. DeCaprio received the Ph.D. degree (1981) in toxicology from Albany Medical College, New York.

Table of Contents

Introduction to Toxicologic Biomarkers. Challenges in the Statistical Analysis of Biomarker Data. Biomarkers of Toxicant Exposure. Biomarkers in Environmental Epidemiology. Use of Biomarkers in Health Risk Assessment. Biomarkers of Toxicant Susceptibility. Identification and Use of Biomarkers in Preclinical Toxicologic Safety Assessment. Use of Biomarkers in Clinical Toxicology and Clinical Trials. Regulatory Guidance and Validation of Toxicologic Biomarkers. Use of Biomarkers in Occupational Safety and Health. Toxicogenomic and Toxicoproteomic Approaches for Biomarkers. Biomarkers of Chemical Warfare Agent Exposure. Applications of Biomarkers in Toxic Tort and Forensic Litigation