Transplant Infections

by Raleigh A. Bowden, Per Ljungman, David R. Snydman

Overview

Transplant Infections is a practical, clinically focused reference covering the common and more unusual bacterial, viral, and fungal infections affecting patients who have received stem cell or solid organ transplants. It provides a comprehensive review of the epidemiology, diagnosis, and management of opportunistic infections and presents strategies for infection prevention and control. Highlights of the Third Edition include a chapter on new immunosuppressive agents and expanded coverage of tropical infections and West Nile virus.

Product Details

ISBN-13:	9781451148091
Publisher:	Wolters Kluwer Health
Publication date:	03/28/2012
Sold by:	Barnes & Noble
Format:	eBook
Pages:	800
File size:	8 MB

About the Author

Bowden, Raleigh A., MD (Fred Hutchinson Cancer Research Center); Ljungman, Per, MD, PhD (Huddinge Univ Hospital); Paya, Carlos V., MD, PhD (Mayo Clinic)

Table of Contents

SECTION ONE: INTRODUCTION TO TRANSPLANT INFECTIONS
Raleigh A. Bowden, Section Editor

1. Introduction to Hemopoietic Stem Cell Transplantation 3
   H. Joachim Deeg and Raleigh A. Bowden
2. Introduction to Solid Organ Transplantation 17
   Barry D. Kahan and Pablo Troncoso

   SECTION TWO: RISKS AND EPIDEMIOLOGY OF INFECTIONS AFTER TRANSPLANTATION
   Carlos V. Paya, Section Editor

3. Risks and Epidemiology of Infections After Allogeneic Hemopoietic
   Stem Cell Transplantation 31
   Kent A. Sepkowitz
4. Risks and Epidemiology of Infections After Autologous Stem Cell Transplantation 39
   Elias Anaissie and Marcio Nucci
5. Risks and Epidemiology of Infections After Heart Transplantation 51
   Susan Keay
6. Risks and Epidemiology of Infections After Lung or Heart–Lung Transplantation 63
   Joan Gavaldá, Antonio Román, and Albert Pahissa
7. Risks and Epidemiology of Infections After Pancreas or Kidney–Pancreas Transplantation 86
   Abhinav Humar and Atul Humar
8. Risks and Epidemiology of Infections After Renal Transplantation 99
   Robert H. Rubin and Nina E. Tolkoff-Rubin
9. Risks and Epidemiology of Infections After Liver Transplantation 120
   Eun Jeong Kwak and Shimon Kusne
10. Risks and Epidemiology of Infections After Intestinal Transplantation 132
    Jorge D. Reyes and Michael Green

    SECTION THREE: SPECIFIC SITES OF INFECTION
    Catherine Cordonnier, Section Editor

11. Pneumonia After Hemopoietic Stem Cell or Solid Organ Transplantation 143
    Catherine Cordonnier and Isabel Cunningham
12. Skin Infections After Hemopoietic Stem Cell or Solid Organ Transplantation 163
    Mazen S. Daoud, Lawrence E. Gibson, and W. P. Daniel Su
13. Central Nervous System Infections After Hemopoietic Stem Cell or Solid Organ Transplantation 175
    Karen L. Roos
14. Liver Infections After Hemopoietic Stem Cell or Solid Organ Transplantation 185
    Ed Gane and Andrew Woodhouse
15. Gastrointestinal Infections After Hemopoietic Stem Cell or Solid Organ Transplantation 198
    George B. McDonald and Michael M. Owens

    SECTION FOUR: BACTERIAL INFECTIONS
    Dan Engelhard, Section Editor

16. Gram-Positive and Gram-Negative Infections After Hemopoietic Stem Cell or Solid Organ Transplantation 225
    Dan Engelhard, Nina Geller, and David L. Paterson
17. Typical and Atypical Mycobacterium Infections After Hemopoietic Stem Cell or Solid Organ Transplantation 250
    Daniel J. Weisdorf
18. Other Bacterial Infections After Hemopoietic Stem Cell or Solid Organ Transplantation 259
    J. Stephen Dummer

    SECTION FIVE: VIRAL INFECTIONS
    Per Ljungman, Section Editor

19. Cytomegalovirus Infection After Hemopoietic Stem Cell Transplantation 277
    Michael J. Boeckh and Per Ljungman
20. Cytomegalovirus Infection After Solid Organ Transplantation 298
    Carlos V. Paya and Raymund R. Razonable
21. Epstein-Barr Virus Infection and Lymphoproliferative Disease After Hemopoietic Stem Cell or Solid Organ Transplantation 326
    Jutta K. Preiksaitis and Sandra M. Cockfield

Editorial Reviews

3 Stars from Doody

This monograph is structured according to infectious agent rather than to bone marrow or specific organ transplant. This provides a comparison and contrast between the two types of transplantation that I found to be extremely helpful and complementary. The purpose is to offer a comprehensive review of epidemiology, diagnosis, and management of opportunistic infections in bone marrow or solid organ transplant patients. This book is written for the medical community at large, not only for transplant physicians and surgeons but for primary care physicians as well. The treatment of viral disease in transplantation is particularly comprehensive and up-to-date. The unique feature is the dedication to transplantation that provides solid recommendations for dose and duration of treatment. This differentiates it from other texts that have treated infections disease in all immunocompromised hosts, including HIV patients, and made it more difficult to obtain specific recommendations for organ transplant recipients who have infections. The specificity of the recommendations make it quite useful for those who are not infectious disease specialists or do not primarily treat transplant recipients. The discussion of the basic bacteriology or virology of each infectious agent is somewhat limited. However, I find this is not a primary shortcoming; in fact, it allows for a more practical focus. If there were any shortcomings, perhaps the discussion of atypical mycobacteria and fungal infections is a bit limited for my own desires given my perception of the increasing incidence of these types of infections in transplant recipients under current immunosuppressive regimens. This is a very useful andreadable treatment of infectious disease in bone marrow and solid organ transplant recipients. I was able to read it cover-to-cover and I found much practical information and very little duplication. I strongly recommend it for anyone who treats or follows bone marrow or solid organ transplant recipients.

Daniel C. Brennan

Brings together information specific to the management of infectious complications that occur specifically in immunocompromised patients undergoing transplantation. Reviews epidemiology, diagnosis, and management of opportunistic infections, focusing on the needs of clinicians at either a hematopoietic stem cell transplant or solid organ transplant center. Material is structured according to infectious agents rather than type of transplant, with specific differences between solid organ transplant types highlighted within the chapter for each infectious agent. Annotation c. by Book News, Inc., Portland, Or.

Booknews

Reviewer: Daniel C. Brennan, MD (Washington University School of Medicine)
Description: This monograph is structured according to infectious agent rather than to bone marrow or specific organ transplant. This provides a comparison and contrast between the two types of transplantation that I found to be extremely helpful and complementary.
Purpose: The purpose is to offer a comprehensive review of epidemiology, diagnosis, and management of opportunistic infections in bone marrow or solid organ transplant patients.
Audience: This book is written for the medical community at large, not only for transplant physicians and surgeons but for primary care physicians as well.
Features: The treatment of viral disease in transplantation is particularly comprehensive and up-to-date. The unique feature is the dedication to transplantation that provides solid recommendations for dose and duration of treatment. This differentiates it from other texts that have treated infections disease in all immunocompromised hosts, including HIV patients, and made it more difficult to obtain specific recommendations for organ transplant recipients who have infections. The specificity of the recommendations make it quite useful for those who are not infectious disease specialists or do not primarily treat transplant recipients. The discussion of the basic bacteriology or virology of each infectious agent is somewhat limited. However, I find this is not a primary shortcoming; in fact, it allows for a more practical focus. If there were any shortcomings, perhaps the discussion of atypical mycobacteria and fungal infections is a bit limited for my own desires given my perception of the increasing incidence of these types of infections in transplant recipients under current immunosuppressive regimens.
Assessment: This is a very useful and readable treatment of infectious disease in bone marrow and solid organ transplant recipients. I was able to read it cover-to-cover and I found much practical information and very little duplication. I strongly recommend it for anyone who treats or follows bone marrow or solid organ transplant recipients.

Doody's Review Service