Treatment of the Postmenopausal Woman: Basic and Clinical Aspects

by Rogerio A. Lobo MD (Editor)

Overview

For anyone who treats postmenopausal women, this latest edition of Rogerio Lobo's classic work combines the best from two well-known references: Menopause, and the second edition of Treatment of the Postmenopausal Woman. By adding significant discussions of the basic science behind menopause, it is possible to objectively assess the clinical value and limitations of current approaches to treatment and provide a basis and rationale for strategies that will result in better individualized and specialized care. Not only does the third edition discuss diagnosis and treatment of menopause but it covers biological, anatomical, physiological, pathobiological, and pharmacological aspects as well bringing together, in one source, all of the information needed to understand and treat postmenopausal conditions.

• Over 50% new material representing the vast amount of information available since the Women's Health Initiative (WHI) clinical trials were completed making this the most up-to-date reference on postmenopausal women
• Includes several new sections on comparisons between clinical trials and observational data, urology, and pelvic support
• Each section is preceded by a preface to put the area into context with many chapters having suggested treatment regimens

Product Details

ISBN-13:	9780080553092
Publisher:	Elsevier Science
Publication date:	06/05/2007
Series:	Menopause Series
Sold by:	Barnes & Noble
Format:	eBook
Pages:	912
File size:	30 MB
Note:	This product may take a few minutes to download.

About the Author

Dr. Lobo, formerly Rappleye Professor and Chair of the Department of Obstetrics and Gynecology, and Director of the Center for Reproductive Sciences, Columbia University, has done extensive research in various areas of reproductive endocrinology and infertility including estrogen metabolism and menopause. Dr. Lobo has a primary interest in hyperandrogenic disorders and polycystic ovary syndrome. He frequently serves as editor for peer-review journals and has authored over 300 articles and 16 books.

Table of Contents

Menopause: A Signal for the Future
Basics to Enhance Our Understanding
Ovarian Senescence&Options
The Perimenopause
Changes Occurring After Menopause
Brain Function
Bone Changes
Cardiovascular (Expanded Intro Section)
Neoplasia
Clinical Trial and Observational Data
Life Cycle and QOL
Urinary Symptoms and Pelvic Support
Hormonal Therapy
Some Alternative Medical Therapies
Women’s Centers, Information Needed for Clinical Trials and the Future

What People are Saying About This

From the Publisher

The best resource in the field, combines research and clinical aspects

Editorial Reviews

This scholarly book covers virtually all aspects of postmenopausal health...Everything is here: the complexity of premature ovarian failure, reproductive options during the perimenopause, the variability in the symptoms of the perimenopause, and the physiology and treatment of hot flashes.
—Ego Seeman

The New England Journal of Medicine

This text is broad in its presentation. Readers who care for menopause-age women will find ample material on physiology, symptom treatment, and health promotion, with accompanying information on the supportive literature.
—Mary Ellen Rousseau

Psychosomatic Research

Reviewer: Tessa E Madden, MD, MPH (Washington University School of Medicine)
Description: This is an extensive review of both the basic science of the menopause, and the provision of clinical care to menopausal or perimenopausal women. Thorough discussions cover the physiologic effects of the menopause and appropriate, evidence-based management. This update of the 1999 edition is appropriate as the results of the Women's Health Initiative (WHI) have greatly impacted hormonal therapy and expanded our knowledge of physiologic changes associated with menopause.
Purpose: The purpose is to provide the scientific basis and rationale for management of menopausal women and the associated symptoms. This is a substantial and growing population in the United States. This edition incorporates the new clinical information from the WHI and it is valuable to have a single book that can serve as a reference for a wide range of topics, from understanding the molecular pharmacology of estrogen and progesterone receptors to alternative medical therapies for menopausal symptoms. In covering a diverse array of topics, the book succeeds in its mission.
Audience: According to the editor, the book is appropriate reading for all providers of women's healthcare and medical professionals in training. I would argue that the intended audience varies from chapter to chapter. Some of the basic science chapters are very dense and may not be appropriate for someone without a strong scientific background, but the chapters with clinical relevance are much more accessible. Dr. Lobo is a well known and respected expert in the field of reproductive endocrinology with over 300 publications.
Features: Chapters covering basic science and research aspects of the menopause transition, including estrogen and progesterone receptors, genetic programming and ovarian physiology begin the book. A thorough and up-to-date chapter details the epidemiology of menopause. Sections cover the varying effects of the menopause on physiologic systems, including cardiovascular, bone, and brain. A further section provides a comprehensive review of observational studies and clinical trials conducted on the effects of hormone therapy. The preface to each section by the editor greatly facilitates understanding of the key points contained in each chapter. A strength of the book is the inclusion of sections on traditional hormone therapy, other medical therapies, and complementary and alternative medicines. It's important for clinicians to be aware of these therapies, since greater numbers of women are choosing to avoid hormone therapy. Unfortunately, there is no discussion of the use of SSRIs for the treatment of menopausal symptoms. The chapter on contraception in older women is important as women over 40 have the second highest rate of unintended pregnancy in the U.S., but it contains outdated information about intrauterine devices (IUD). In addition, a discussion about use of the levonorgestrel IUD to protect the endometrium in women taking hormone therapy is lacking, particularly as the evidence suggests the addition of oral progesterones is problematic.
Assessment: Overall, this is an extremely useful and pertinent reference for any clinician providing care to peri- and postmenopausal women and competes as one of the most comprehensive and current menopause books available. The new edition is timely as we incorporate the WHI results and the lessons learned about hormonal therapy into our practices and our management of women in the menopause.

Doody's Review Service