Vascular Manifestations of Systemic Autoimmune Diseases / Edition 1

by Ronald A. Asherson, Ricard Cervera, Douglas A. Triplett, Steven B. Abramson

Overview

Not too long ago, it was thought that inflammation of blood vessels was the sole manifestation of systemic autoimmune diseases. Today, however, we know that disorders of coagulation, injuries to both neutrophils and endothelial cells, and certain lipids and amino acids are all intricately involved in the development of vascular disease. How are all these processes linked? What'strategies can we employ or develop to halt the progression of vascular damage? What are the best ways to control acute vasculitis and vasospasm therapeutically? What are the risks and benefits of various strategies for the prevention of clotting? How soon should we initiate preventive strategies that protect blood vessels from arteriosclerosis in people with acute rheumatic diseases? What's should be the nature of those strategies?

Vascular Manifestations of Systemic Autoimmune Diseases provides answers to all these questions. Ronald Asherson, Richard Cervera,Steven B. Abramson, Jean-Charles Piette, and Douglas Triplett- all international experts in the field-have assembled a collection of works that provide a comprehensive analysis of vascular irregularities. Now that most individuals survive the onset of acute systemic autoimmune diseases and live for decades more, halting the long-term attack on vasculature is increasingly important.
Vascular Manifestations of Systemic Autoimmune Diseases not only describes the clinical symptoms of vascular diseases; it also covers in one volume the many mechanisms involved in the pathogenesis of these disorders and addresses the newest treatments available for them.

Product Details

ISBN-13:	9780367397616
Publisher:	Taylor & Francis
Publication date:	09/11/2019
Edition description:	Reprint
Pages:	624
Product dimensions:	7.00(w) x 10.00(h) x (d)

About the Author

Ronald A. Asherson, Ricard Cervera

Table of Contents

Section I: Mechanisms of Vascular Disease. Section II: Clinical Manifestations. Section III: Treatment.

Editorial Reviews

Reviewer: Deborah Jane Lenschow, MD, PhD (Washington University School of Medicine)
Description: This book provides a detailed analysis of the mechanisms involved in the pathogenesis of vascular injury and applies these concepts to the vasculitic syndromes treated by clinicians. It also focuses on the current therapeutic interventions that target these autoimmune disorders and the vascular injury that occurs.
Purpose: The editors and a panel of expert clinicians and scientists provide a detailed analysis of the clinical syndromes associated with vascular injury and the current mechanisms responsible for disease pathogenesis.
Audience: This is a resource to assist clinical trainees and practicing rheumatologists gain a better understanding of the mechanisms responsible for vascular injury and how these relate to the systemic rheumatologic disorders we treat.
Features: In the first section, the basic biological mechanisms known to cause vascular injury are discussed. In the following sections, these findings are applied to the clinical presentation of a variety of systemic autoimmune diseases and to the specific therapies for these disorders. The final section covers the most up-to-date treatment strategies used by clinicians in the management of these disorders.
Assessment: This book integrates the current understanding in the field of the biology underlying these varied vasculitic syndromes with their clinical presentations and the therapeutic strategies used to treat them.

Doody's Review Service