Visualizing Disease: The Art and History of Pathological Illustrations

Visualizing Disease: The Art and History of Pathological Illustrations

by Domenico Bertoloni Meli
Visualizing Disease: The Art and History of Pathological Illustrations

Visualizing Disease: The Art and History of Pathological Illustrations

by Domenico Bertoloni Meli

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Overview

Visual anatomy books have been a staple of medical practice and study since the mid-sixteenth century. But the visual representation of diseased states followed a very different pattern from anatomy, one we are only now beginning to investigate and understand. With Visualizing Disease, Domenico Bertoloni Meli explores key questions in this domain, opening a new field of inquiry based on the analysis of a rich body of arresting and intellectually challenging images reproduced here both in black and white and in color.
 
Starting in the Renaissance, Bertoloni Meli delves into the wide range of figures involved in the early study and representation of disease, including not just men of medicine, like anatomists, physicians, surgeons, and pathologists, but also draftsmen and engravers. Pathological preparations proved difficult to preserve and represent, and as Bertoloni Meli takes us through a number of different cases from the Renaissance to the mid-nineteenth century, we gain a new understanding of how knowledge of disease, interactions among medical men and artists, and changes in the technologies of preservation and representation of specimens interacted to slowly bring illustration into the medical world.

Product Details

ISBN-13: 9780226110295
Publisher: University of Chicago Press
Publication date: 01/19/2018
Pages: 288
Product dimensions: 7.20(w) x 10.20(h) x 1.00(d)

About the Author

Domenico Bertoloni Meli is provost professor of history and philosophy of science and medicine at Indiana University, Bloomington.
 

Read an Excerpt

CHAPTER 1

VISUALIZING DISEASE IN THE EARLY MODERN PERIOD

This chapter explores some key themes related to the visual representation of disease in the early modern period by combining a thematic and a biographical approach. I focus on three major aspects; the new genre of Observationes and the cognate Historiae and Curationes, especially those marked as chirurgicae, offered a venue for focusing on case histories. The establishment of anatomical museums and collections including pathological specimens provided valuable material for instruction and comparison; this practice accelerated in the last third of the seventeenth century, with the development of novel preservation techniques. Finally, the rise of surgeons socially and in the main scientific societies of the time favored what I call a "doubly localistic" approach valuing visualization; while of course visual representations of diseased states were not the exclusive prerogative of surgeons, it was surgeons who played an especially prominent role both directly and indirectly, by promoting and advocating their perspective. These developments intersected and reinforced each other.

Two figures emerge as particularly significant at the endpoints of my account, Guilhelmus Fabricius Hildanus in the first third of the seventeenth century and Frederik Ruysch in the decades around 1700. While Ruysch is well known and has attracted a considerable amount of scholarship in recent years, Fabricius has been far less studied, despite his reputation at the time. Their activities touched on the three themes I have identified: despite major differences in the preservation methods available at their respective times, both established museums that have been carefully documented; Fabricius was a leading surgeon, while Ruysch was lecturer to surgeons; their publications include collections of Observationes, rely on their museums, and present a large number of illustrations, including pathological ones.

Preamble: Early Broadsides and Surgical Treatises

Publications with illustrations of diseased states came in different formats, from folio to duodecimo and from large collections to small ephemeral broadsides. Here I wish to provide a few introductory remarks about very early developments with no pretense to offering a comprehensive treatment. It may come as no surprise that up to the sixteenth century the most common form representation associated to disease was the uroscopy chart, often depicted in the form of a wheel with many beautifully hand-colored urine flasks. Such charts provided a careful description of color, whose role in ascertaining disease was discussed in the text in relation to the four humors, blood, yellow bile, black bile, and phlegm. The many editions and translations of Fasciculus medicinae (editio princeps, Venice, 1491) by German physician Johannes de Ketham, for example, included a uroscopy chart with over twenty flasks. Such charts, however, represent diseased states only in an indirect way; although their role declined in the sixteenth century, they show that physicians included images, even colored ones, when they perceived them to be intellectually significant to their practice.

Broadsides were a popular print form often announcing monsters, portents, and marvels. The spread of the French pox at the end of the fifteenth century constituted a dramatic development; the depiction attributed to Albrecht Dürer of a victim of the disease in a 1496 broadside by the Nuremberg town physician Theodoricus Ulsenius was probably the first of its kind. It shows the victim flanked by Nuremberg's coats of arms under a zodiac sign with the year 1484, pointing to the astrological cause of the condition. Even when the broadside was hand-colored, the visual clues remained rather general at best. In the early Renaissance broadsides rarely provided detailed visual representations of diseased states; their main focus was elsewhere, often with congenital malformations perceived as monstrous.

Surgery is the medical specialty with an especially strong association with visual representation. Unlike physicians, surgeons used many mechanical tools and took pride in them: instruments are often given a prominent role in their treatises. Procedures too are often featured and provide rich documentation about wider issues such as venues and social status. Surgical operations before the mid-nineteenth century were limited: they involved removing external growths and tackling external and rarely some internal conditions, such as those associated with syphilis, for example, the urinary system, amputations, and bone afflictions. Moreover, surgeons were often the ones responsible for dissections and would therefore have been in the front line at postmortems. Overall, however, early surgical works focused more on instruments and procedures than on diseased states as such, and when these do appear, they tend to be rather schematic, though matters progressively changed.

At a time when images in medical books were emerging, they may have served a variety of didactic and practical purposes: the precise shape of surgical instruments would be practically relevant but also advertise the surgeon's skill and equipment. Images of successful cures would obviously advertise the medical man's skill. Procedures would show the proper set-up for patients and surgeons in a way that could be difficult to describe in words. Lastly, some images may have had a decorative or a mnemonic purpose, as the "wound-man," with his impossibly large number of conditions, frequently shown in surgical works.

Feldtbüch der Wundtartzney (Strassburg, 1517) by military surgeon Hans von Gersdorff (ca. 1455–1529) is remarkable as an early example of both anatomical and pathological illustrations. Several plates in this surgery book show unusual attention to pathological conditions in live patients. Historian LukeDemaitre has argued that the woodcut of a leprosy patient in the Feldtbüch shows several procedures that would have unlikely occurred simultaneously (illustration 1.1). On the left possibly a barber surgeon washes a cloth that has been soaked in the patient's blood; finding a sandy residue, or perhaps adherence of the blood to its container, would be a sign of leprosy. The two small cups in the foreground possibly contained salt and vinegar for assaying the blood by ascertaining whether it dissolved salt and whether vinegar changed its color. The patient, dressed in loose garments and in a pose reminiscent of Jesus surrounded by his tormentors, is being examined by a surgeon palpating his forehead while turning away to confer with the other people in attendance; his expression seems to express disgust at the patient's stench, this being another diagnostic sign. Nodules are shown at different locations on his body, especially on the face, where they were deemed indicative of leprosy, but they are rendered schematically and without much detail. The next person on the right may be another physician or a public official; the last one on the right is a physician shown canonically while examining the urine flask. Overall, the nature of the condition is identified more by the text and setting than the actual lesions.

The later sixteenth century witnessed the appearance of major surgical works from such iconic figures as Ambroise Paré, surgeon to several French kings, Guido Guidi, active between Italy and France, Venice surgeon Giovanni Andrea della Croce, and Dresden oculist Georg Bartisch. Despite the exceptional quality and interest of some of the plates, overall their subjects eschew detailed representations of lesions. Guidi's Chirurgia (Paris, 1544), for example, is an edition of ancient surgical works including images of conditions such as dislocations from the original manuscripts. Bartisch's Ophthalmodouleia, oder Augendienst (1583), an ophthalmology treatise with numerous illustrations drawn by the author, includes images of instruments and procedures and occasionally also representations of eye diseases.

Collecting and Visualization in Fabricius Hildanus

An especially significant figure in my story is Guilhelmus Fabricius from Hilden, or Hildanus (1560–1634), a prominent learned surgeon of his time. His publications in both Latin and the vernacular and extensive epistolary exchanges with prominent figures testify to his status. Fabricius lived a large portion of his life in Switzerland, first Geneva, then Payerne, and eventually Bern, where he became town surgeon and physician. Starting from the end of the sixteenth century, he published several works, notably a series of six centuriae of Observationes et curationes chirurgicae with many illustrations, and treatises on gangrene and dysentery; his Latin Opera (Frankfurt/M, 1646) was translated into French by Bonet in 1669, and a new revamped Latin edition appeared as late as 1713.

Fabricius followed contemporary practices of learned physicians by publishing collections of Observationes and establishing a museum; in both areas, however, he adopted a surgical approach to documenting his practices and perspectives. He was among the first to characterize his Observationes as chirurgicae as opposed to medicae. Observationes were a new genre that emerged in the mid-sixteenth century, as Gianna Pomata has shown. They stem from the empirical tradition and focus on individual cases; they could make an unusual condition known to the medical community or advertise the success of the medical man in a difficult case. While following this tradition, Fabricius also developed it in new ways. Unlike their medical counterpart, surgical observationes focused on the manual intervention of the surgeon, often involving specially designed instruments that were illustrated together with the specific form of a growth, whether still attached to the body or removed; stones found in the bladder, kidneys, gallbladder, or other body parts; and broken or healed bones. Similarly, following the example of several Italian medical men and contemporary physicians and correspondents at Basel, such as Felix Platter (1536–1614), Caspar Bauhin (1560–1624), and Jacob Zwinger (1569–1610), Fabricius assembled a museum, which was located in his home; although we know that he also collected ancient coins, in his correspondence and publications he singled out a cohesive body of anatomical, surgical, and pathological items.

Besides describing and at times providing images of several items in his Observationes, Fabricius left a detailed description of his museum in a letter to Leiden anatomist Pieter Paaw, including some of his preservation methods. At the time Leiden had an anatomical museum that Fabricius had visited. A few decades before Fabricius, Paré had used vinegar and alcohol for preservation, but his aim seems to have been embalming more than saving body parts for scholarly purposes. Fabricius relied on drying and stuffing cavities, from blood vessels to the digestive tract, with hemp and cotton. He also mentioned a white mole and a monstrous black sow preserved with aloe, myrrh, scordium, absinth, and hemp.

With such limited preservation methods, it is not surprising that his museum consisted largely of stone formations and especially bones, both being largely surgical domains. All the items listed in his letter to Paaw were naturalia, except for an artificial eye he had constructed; he listed forty-eight individual items or collections of items — item twenty-three, for example, mentions more than thirty badly healed bones — for a total exceeding one hundred. The main organization criterion emerging from his letter to Paaw is the distinction between human and animal items: the first twenty-nine items list human parts, whether healthy or diseased, items thirty to forty-eight relate to a wide range of animals, which would display an analogy, proportion, and similarity with the human body. Very small animals display God's knowledge, providence, and goodness; thus Fabricius's museum joined cognitive and religious motivations. One item, thirty-seven, consists of a "monstrous" pig with double parts; Fabricius also wrote a pamphlet on a monstrous sheep, though it was not included in his Opera, where overall monsters do not play a significant role.

Fabricius included a large number of images in his works. Much like rare and remarkable specimens in his museum, or successful cures reported in Observationes, images enhanced his standing and provided valuable material for investigation and instruction. No doubt, they added to the appeal of a work for multiple reasons; in discussing the peculiar position of a fetus Fabricius defended their cognitive role, arguing that features that "are obscure from a description, can be better known from an image." Some passages point to Fabricius relying on draftsmen, at times including noted Bern artist Joseph Plepp.

The first case in Fabricius's Opera dates from 1596 and discusses the eye tumor of Claude Mayor of Lutry, a small town on the lake near Lausanne. The prominence of the patient and the difficulty of the case led Fabricius to devote over twelve folio pages and several woodcuts to its description. He discussed the case history and instruments employed but also diet and evacuations in preparation for the operation, these being often the domain of physicians. The woodcut (illustration 1.2) juxtaposes separate stages, showing the patient with his affected eye, the successfully extirpated tumor lying on the table, and one of the implements used. The status of the patient appears from his sumptuous robes, while the size of the tumor induces wonder in the viewer today, as it must have done at the time; both aspects were clearly self-advertisements. The plate is representative of early surgical works, which often included external growths that were among the main areas accessible to surgical treatment.

This woodcut is lacking in the early 1598 and 1606 editions; it first appeared posthumously, leaving one to wonder whether Fabricius had a drawing made at the time or whether the image is a retrospective creation. Either way, its publication history reminds us that we should not take such images for granted. In fact, there are substantive differences between editions published during his lifetime and the posthumous 1646 Opera. Occasionally we have the drawings from which the printed images were produced, at times in color. For example, in 1611 Fabricius discussed a mola, a fleshy mass found in the pregnant uterus; although he could not reproduce it full size for reasons of space, it being almost the size of an infant's head and the book being a small octavo, he stated that the original could be seen in his museum. The Opera is much larger than the 1611 edition, and although the image takes only a portion of the page, the passage is unchanged. The 1646 image differs considerably from the original drawing and the 1611 version. Although the original report on the case dates from 1607, the mola is not mentioned in the description of his museum, possibly because it had decayed beyond redemption by then, since it was already "semiputrida" from the start.

An intriguing woodcut raises questions about Fabricius's practices. It relates to an eleven-year-old girl from Köln who had died in 1595 but was first published in 1611, in the second centuria of Observationes. The girl suffered from a fever that was first ephemeral and then became hectic — involving daily spikes and night sweats. Several symptoms were explained by the postmortem, performed by Fabricius in the presence of a surgeon and an apothecary; difficulty in speaking, deglutition, and breathing, for example, were attributed to a fatty and fleshy lump attached to the trachea. The postmortem revealed an infestation of intestinal worms and a number of chalky formations affecting many parts; the lungs were filled with festering fatty matter, the size of a walnut or chestnut. The plate shows the longitudinally sectioned spleen with symmetric chalky formations that seemingly attracted the artist's attention (illustration 1.3). It is unclear whether this image was recreated from memory, or whether Fabricius had a drawing made at the time, thus suggesting that he collected not only specimens but also images of remarkable and unusual cases. We do not know why he chose the spleen, since several other body parts showed similar features. In the nineteenth century German pathologist Hermann Lebert convincingly characterized Fabricius as a surgeon rather than an anatomo-pathologist. Nonetheless, this plate is an especially early representation of a diseased internal organ, and as such it calls for an explanation. Possibly Fabricius was intrigued by the peculiar pathological formations and their links with the patient's symptoms, or he saw these reports as an advertisement to his extensive experience in postmortems, which were routinely performed by surgeons. Either way, the plate is unique in Fabricius's published works and exceptional for the standards of the time.

(Continues…)



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Table of Contents

Preface

Introduction: Bodies, Diseases, Images
Chapter 1. Visualizing Disease in the Early Modern Period
Chapter 2: “Sic nata est anatome pathologica picta”: The Diseases of Bones
Chapter 3. Preserved Specimens and Comprehensive Treatises
Chapter 4. Intermezzo: Identifying Disease in Its Inception
Chapter 5. The Nosology of Cutaneous Diseases
Chapter 6. Morbid Anatomy in Color
Chapter 7. Comprehensive Treatises in Color
Concluding Reflections
 
Acknowledgments
Illustration Credits
List of Abbreviations
Notes
Bibliography
Index

What People are Saying About This

Russell Maulitz

"A work that was crying out to be written. Exhaustive, learned, and a gold mine for specialists, yet wholly accessible for nonspecialists. And in a field—anatomical pathology—that's not lent itself easily to graphical exposition, Bertoloni Meli's volume is just gorgeous in its pictorial depiction of changing notions of disease."

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