Table of Contents
List of Contributors xiii
Foreword xix
Preface xxi
About the Companion Website xxiii
Section 1 Basic Science 1
1 Introduction 3Somesh Gupta and Nanja van Geel
2 Melanocyte and Melanogenesis: Applied Anatomy and Physiology 9Reinhart Speeckaert and Nanja van Geel
3 Epidemiology of Vitiligo 15Nader Aboul‐Fettouh and Amit G. Pandya
4 Pathogenesis of Vitiligo 19John E. Harris
5 Understanding the Mechanisms of Repigmentation in Vitiligo 27Ravinder Kumar, Davinder Parsad, and Amrinder J. Kanwar
Section 2 Clinical Science 33
6 Classification and Clinical Features of Vitiligo 35Sang Ho Oh and Seung‐Kyung Hann
7 Outcome Measures for Vitiligo 49Brian Clinton, Viktoria Eleftheriadou, Nanja van Geel, Laila Benzekri, Amit G. Pandya, and Khaled Ezzedine
8 Evaluation and Treatment of the Psychosocial Burden of Vitiligo 61Vishal Gupta and M. Ramam
9 Patient Support, Education, and Compliance 69Richard H. Huggins, Jackie Gardner, and Amit G. Pandya
10 Goals of Vitiligo Treatment, and Evidence‐Based Practice Guidelines for Medical and Surgical Management 77Kevin Prier and Amit G. Pandya
11 The Concept of Stability of Vitiligo and Stabilization Therapies 81Anuradha Bishnoi and Davinder Parsad
Section 3 Phototherapy 91
12 Narrow‐Band Ultraviolet B Phototherapy in Vitiligo 93Narumol Silpa‐archa and Henry W. Lim
13 UVA‐Based Phototherapy: PUVA, PUVA‐Sol, and UVA1 Phototherapy 105Ljubomir B. Novaković
14 Targeted Phototherapy in Vitiligo 113Mohammed Al‐Jamal, James L. Griffith, Iltefat H. Hamzavi, and Henry W. Lim
Section 4 Medical Management 123
15 Immunomodulators and Immunosuppressives in Vitiligo Treatment 125Anuradha Bishnoi and Davinder Parsad
16 Topical Glucocorticoids, Topical Calcineurin Inhibitors, and Topical Vitamin D3 Analogs 133Sai Yee Chuah and Boon Kee Goh
17 Other Therapies in Vitiligo 141Narumol Silpa‐archa, James L. Griffith, Iltefat H. Hamzavi, and Pearl E. Grimes
18 Biologic Therapies for Vitiligo 151Pablo Michel and Amit G. Pandya
19 Evidence Toward Integrated Management of Vitiligo, Combining Ayurveda and Homeopathy with Modern Dermatology 159Saravu R. Narahari, Madhur G. Aggithaya, Kuthaje S. Bose, and Kodimoole S. Prasanna
Section 5 Surgical Therapies: History, Patient Selection, and Classification 171
20 History and Chronology of Development of Surgical Therapies for Vitiligo 173Koushik Lahiri and Abhishek De
21 Patient Selection, Pre‐ and Postoperative Information in Surgical Therapies for Vitiligo 185Nanja van Geel and Mats J. Olsson
22 Classification of Surgical Therapies in Vitiligo 193James L. Griffith, Mohammed Al‐Jamal, and Iltefat H. Hamzavi
Section 6 Surgical Therapies: Tissue Grafting 209
23 Minigrafting for Vitiligo 211Koushik Lahiri
24 Suction Blister Epidermal Grafting 225Savita Yadav and Somesh Gupta
25 Thin and Ultra‐Thin Skin Grafts for Vitiligo 241Imran Majid
26 Treatment of Leukoderma by Transplantation of Ultra‐Thin Epidermal SheetsUsing a Motorized Dermatome 249Mats J. Olsson
27 Mesh Grafts for Vitiligo 257Chakravarthi R. Srinivas and Reena Rai
28 Smash Grafting 261Sumit Kar, Ajay Krishnan, and Sudhir Singh
29 Therapeutic Needling and Needling Micrografting 267Khalifa E. Sharquie and Adil A. Noaimi
30 Complications and Limitations of Melanocyte Transplantation 273Yvon Gauthier and Laila Benzekri
Section 7 Surgical Therapies: Cellular Grafting 279
31 Treatment of Leukoderma by Transplantation of Basal Cell Layer Suspension 281Mats J. Olsson
32 Non‐Cultured Extracted Follicle Outer Root Sheath Cell Suspension Transplantation 293Kanika Sahni and Somesh Gupta
33 Long‐Term Results of Non‐Cultured Epidermal Cellular Grafting in Vitiligo 299Nanja van Geel, Sofie De Schepper, Hilde Lapeere, Barbara Boone, Boon Kee Goh, and Reinhart Speeckaert
34 Simplified Non‐Cultured Cellular Grafting 303Boon Kee Goh
35 Novel Methods of Preparing Epidermal Cell Suspension for Transplantation in Vitiligo 309Vishal Gupta, Sanjeev Gupta, Kanika Sahni, and Somesh Gupta
36 Management of Vitiligo: Setting Up a Tissue Culture Laboratory 317Rafał Czajkowski, Małgorzata Maj, and Tomasz Drewa
37 Treatment of Leukoderma by Transplantation of Cultured Autologous Melanocytes 323Mats J. Olsson
38 Transplantation of In‐Vitro‐Cultured Epithelial Grafts for Vitiligo and Piebaldism 337Liliana Guerra, Sergio Bondanza, and Desanka Raskovic
39 Application of Lasers for Abrasion in Transplantation Procedures for Vitiligo 351Gwang Seong Choi
40 Cell Delivery on Recipient Skin 357Thomas Hunziker
41 Safety Concerns in Transplantation of In‐Vitro‐Cultured Cellular Grafts 363Liliana Guerra, Elena Dellambra, Patrizia Paterna, and Somesh Gupta
Section 8 Special Issues in Medical and Surgical Therapies 369
42 Surgical Management of Vitiligo of Lips, Eyelids, and Genitals 371Riti Bhatia and Somesh Gupta
43 Surgical Management of Acral Vitiligo 389Munish Paul
44 Surgical Management of Leukotrichia 401Amrendra Kumar
45 Surgical Treatments of Leukodermas Other Than Vitiligo Vulgaris 407Mats J. Olsson
46 Ethnic Issues in Management of Vitiligo and Sun Protection 417Haneol S. Jeong, Michelle Rodrigues, and Amit G. Pandya
47 Management Issues for Vitiligo in Children and Pregnant Women 427Freya Van Driessche and Nanette Silverberg
48 Combination Treatments for Vitiligo 439Anuradha Bishnoi and Davinder Parsad
49 Micropigmentation 451Gurvinder P. Thami
50 Camouflage in Vitiligo 459Chakravarthi R. Srinivas, Pradeep Balasubramanian, and C.K. Shashidharan Nair
51 Depigmentation Treatment for Vitiligo: Bleaching Cream, Laser, and Cryotherapy 469Nanja van Geel and Monique R.T.M. Thissen
52 Future Directions in the Treatment of Vitiligo 475Vishal Gupta and Somesh Gupta
53 Informed Consent 491Mats J. Olsson
Index 495