Landmark Papers in Pain: Seminal Papers in Pain with Expert Commentaries

by Paul Farquhar-Smith (Editor), Pierre Beaulieu (Editor), Si?n Jaggar (Editor)

Overview

Pain Medicine, a relatively new specialty, has proven increasingly relevant to medical practitioners in every field. The specialism of pain has emerged over the past 50 years, largely due to the persistence of experts and new medical evidence that points to its necessity. Today, it is a distinct and integral part of global medical practice. Landmark Papers in Pain offers a comprehensive inventory of over 80 key studies in pain medicine from the last 100 years. Each paper is accompanied by a concise commentary on the significance of the original findings written by an expert in pain. The reviews discuss how the paper influenced the development of the speciality, and how the findings have advanced our global comprehension of pain. Together, the selected papers and reviews chart the growth of an embryonic field into the modern speciality of pain medicine. Complied by leading specialists in the field, the papers included in this book are significant for any student, researcher, clinical practitioner, or medical historian interested in pain medicine. Organised into eight distinct topics and cross-referenced by topics and author of original paper, the book is comprehensive in its coverage and easy to use. A review of the contemporary and historical research that shaped the speciality of pain, Landmark Papers in Pain is essential reading for all medical practitioners with an interest in pain medicine.

Product Details

ISBN-13:	9780191057250
Publisher:	OUP Oxford
Publication date:	07/18/2018
Series:	Landmark Papers In
Sold by:	Barnes & Noble
Format:	eBook
Pages:	320
File size:	2 MB

About the Author

Dr Paul Farquhar-Smith, MA, MB, BChirFRCA, PhD, FFPMRCA, FFICM, is at present a Consultant in Pain Medicine and Anaesthesia at The Royal Marsden NHS Foundation Trust in London, UK. He specialises in pain in cancer patients and survivors (post-surgical chronic pain, chemotherapy induced neuropathy), and anaesthesia for breast and reconstructive surgery. Dr Pierre Beaulieu is at present a Professor of Anesthesiology and Pharmacology at Universit? de Montr?al in Canada. He specialises in the pharmacology and neurobiology of pain, the use of cannabinoids for treatment of pain, and in local anaesthetics Dr Si?n Jaggar is at present a Consultant in Anaesthesia at Royal Brompton&Harefield NHS Foundation Trust in London, UK. She specialises in adult and paediatric cardiothoracic anaesthesia and pain relief. She has a particular interest in education as a tool to enhance understanding between different working groups. She is the Royal College deputy regional advisor for the North West Thames region and the lead for less than full time trainees in this region.

Table of Contents

Section 1: Historical
1. Local anaesthetic substitutes for cocaine, JAW (Tony) Wildsmith
2. Innovative concepts in pain management, Ben M. Thomas
3. Explaining reflex sympathetic dystrophy, Sebastian Brandner and Brigitta Brandner
4. The rediscovery of paracetamol, Alain Eschalier and Christophe Mallet
5. The pharmacology of placebos, Fabrizio Benedetti
6. Understanding the responsiveness of c-fibres, Jean-Sebastien Walczak
7. A new theory of pain, Tony Dickenson
8. Three determinants of pain, Manon Choiniere and Gabriella Page
9. Purinergic nerves: a new type of nerve, Guy Rousseau
10. Genetic differences in opiate receptors, Jeffrey S. Mogil
11. Endogenous opioids in placebo-induced analgesia, Pierre Rainville
12. Ethical pain experimentation in conscious animals, Eric Troncy
13. Local anaesthetic creams, Argyro Fassoulaki
14. The backpain revolution, Cathy Price
15. The mechanism of aspirin, Pierre Sirois and Pedro D'orleans-Juste
16. Mechanisms of visceral pain in IBS, Yasser Al Omran and Qasim Aziz
17. The effects of morphine on the central nervous system, Philippe Richebe and Cyril Rivat
18. Opiods in palliative care, Joan Hester
19. Endogenous opiods in the central nervous system, Tony Dickenson
20. Spinal opioid analgesia in the rat, Craig W. Steven
Section 2: Firsts
21. The key role of NGF in inflammatory pain processing, Paul Farquhar-Smith
22. Mapping of neurotrophin receptors on adult sensory neurons, Elizabeth J. Bradbury
23. Plasticity in somatic receptive fields after nerve injury, Stephen R. Humble
24. Peripheral neural mechanisms of cutaneous hyperalesia and heat pain, Amanda Klein and Matthias Ringkamp
25. The Cloning and Characterization of CB1, Mary E. Abood and Thomas Gamage
26. Deorphanisation of ORL-1/LC132 by reverse pharmacology in two landmark studies, Mark F. Bird and David Lambert
27. The capsaicin receptor, Istvan Nagy
28. Vanilloid receptor 1 in inflammatory thermal hyperalgesia, Istvan Nagy
29. A signature of pain in the brain, Pierre Rainville
30. Cytokines as central to peripheral sensitisation and hyperalgesia, John Schutzer-Weissmann
31. Endogenous opioids mediate stress-induced analgesia, Claudia Sommer
32. The first crystal structure of an iGluR ligand-binding core, Ke Ren and Ronald Dubner
33. Control of pain initiation by endogenous cannabinoids, Andrea Hohmann
34. Peripheral Analgesia involves Cannabinoid Receptors, Julie Desroches
35. Glia: a new pain target, Marzia Malcangio
36. The challenges of animal models of pain, Bradley Kerr and Muhammad Saad Yousuf
37. Mechanisms of bone cancer pain, Philippe Sarret
38. Molecular Structure of the Mu-Opioid Receptor, Roger Knaggs
39. Milestone Effect of DNIC in our Understanding of Pain, Serge Marchand
40. Original description of central sensitisation, Sheila Black
41. Molecular basis for Placebo effect, Lesley Bromley
Section 3: Science
42. Early discussions on an mechansitic approach to pain, Robert D. Searle
43. Plasticity: a kew concept in pain, Alfredo Ribeiro Da Silva and Claire Magnussen
44. The importance of descending modulatory pain systems, Enrique Collantes
45. Nocebo and its importance in clinical practice, Helen Laycock
46. Mechanisms of Action of Acetaminophen for Pain Treatment, Pierre Beaulieu
47. Making the link from central sensitization to clincal pai, Juergen Sandkuehler
Section 4: Clinical
48. Proof of concept: epidural morphine, Vicky Tidman
49. The Definition of Fibromyalgia, Mike Shipley
50. The advent of PCA for post operative analgesia, Suzanne Chapman
51. Undertreatment of pain with metastatic cancer, Matthew J. Allsop and Michael Bennett
52. Faces scales in paediatric pain assessment, Alison Bliss
53. Epidural block and phantom limb pain, Stephan Schug
54. Clarifying the concept of Breakthrough pain, Giovambattista Zeppetella
Section 5: Mechanisms
55. Paediatric pain epidemiology, Alison Bliss
56. Recognising the importance of HIV disease and pain, Peter Kamerman
57. The additive analgesia of adrenaline in epidural blockade, Andrew N. Davies
58. The additive analgesia of adrenaline in epidural blockade, Paul Farquhar-Smith
59. What is the clinical relevance of the Likert scale for pain?, Felicia Cox
60. Post operaitve pain: assessing the standards, Jane Quinlan
61. Opioid induced hyperalgesia, Kirsty Bannister
62. CRPS epidemiology, Naomi Scott
63. Seminal paper on epidemiology of cancer pain, Paul Farquhar-Smith
64. Endoscopic ultrasounfd guided coeliac plexus block, Arun Bhaskar
Section 6: Neuropathic
65. Autotomy: an early neuropathic pain model, Elizabeth Bradbury
66. Risk factors for post amputation pain, Tudor Phillips
67. Chronic constriction injury (CCI) model of neuropathic pain, Matthew Brown
68. Antineuropathic medication combinatoin therapy, Mick G. Serpell
69. RCT evidence for gabapentin in post herpetic neuralgia, Rajesh Gupta
70. Idenitifcation of the target of gabapentinoid action in neuroapthic pain, Turo J. Nurmikko
71. Recognition of the importance of Neuropathic pain epidermiology, Matthew Brown
72. Botox analgesia for neuropathic pain, Abdelghani Mowafak
73. DNIC and prediction of chronic post surgical pain, Sibtain Anwar
74. Pregabalin in the reduction of chronic post knee surgery chronic pain, Richard M. Langford
75. Multidisciplinary Cognitive Behavioural Treatment for Chronic Pain, Toby Newton John
76. Disability in Chronic Low Back Pain, Rakesh Jain
Section 7: Psychosocial
77. The Understanding of Social Effects in Pain, Amanda Williams
Section 8: Genetics
78. Congenital insensitivity to pain, Bhagat Singh, Alban Latremoliere and Michael Costigan
79. Polymorphic CYP2D6 as the Responsible Enzyme of Activation, Ingolf Cascorbi
80. COMT genotypes in pain responses, Matthew Hamilton
81. The link between NaV1.7 mutation and erythromelelgia, Bradley J. Kerr
82. COMT and morphine use in cancer pain, Fausto Morell-Ducos
83. Pinoeering use of gene thearpy for pain, Roman Cregg